Commentary on Wu and Ma.

Fisher (1947) and Bailey (1961) considered a two-locus tetrasomic model and exploited the basic features of genetic segregation and linkage of tetrasomic inheritance. They attempted to establish the relationship between the model parameters (the coefficients of double reduction at two linked loci, say α and β respectively, and recombination frequency between them, r) and frequencies of gamete modes. However, it was clearly pointed out in Bailey (1961, page 113) that “so far there is no theoretical basis for predicting the frequency of any given mode of gamete formation in terms, for example, the recombination fraction between the two loci and the two double reduction parameters”. Under exactly the same model, we were able to present the frequency of any given mode of gamete formation in terms of the genetic parameters and to establish an intrinsic relationship between the three parameters in the form given by